GTX81222
PERK antibody, N-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX81222
- Zusätzliche Namen:
- eukaryotic translation initiation factor 2 alpha kinase 3 , PEK , PERK , WRS
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- SAS Precipitated; Dialysis
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.09% Sodium azide.
- Immunogen:
- KLH conjugated synthetic peptide between 148-175 amino acids from the N-terminal region of human PERK.
- Uniprot:
- Q9NZJ5
- Synonyme:
- eukaryotic translation initiation factor 2-alpha kinase 3;pancreatic EIF2-alpha kinase;PEK;PERK;PRKR-like endoplasmic reticulum kinase;truncated eukaryotic translation initiation factor 2 alpha kinase 3;WRS
- Weitere Details:
- The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]
- Versandbedingungen:
- Blue Ice