ALDH18A1 antibody, Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX80929
Zusätzliche Namen:: aldehyde dehydrogenase 18 family member A1 , ADCL3 , ARCL3A , GSAS , P5CS , PYCS , SPG9 , SPG9A , SPG9B
Anwendung:: Flow Cytometry, WB, IHC-P
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified; Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 0.09% Sodium azide.
Immunogen:: KLH conjugated synthetic peptide between 176-205 amino acids from the Central region of human ALDH18A1.
Uniprot:: P54886
Synonyme:: ADCL3;aldehyde dehydrogenase family 18 member A1;ARCL3A;delta-1-pyrroline-5-carboxylate synthase;delta-1-pyrroline-5-carboxylate synthetase;delta1-pyrroline-5-carboxlate synthetase;GSAS;P5CS;PYCS;pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase);spastic paraplegia 9 (autosomal dominant);Spastic paraplegia-9 (spastic paraparesis with amyotrophy, cataracts and gastroesophageal reflux);SPG9;SPG9A;SPG9B
Weitere Details:: This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice