RPB1 antibody [4H8]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX80341
Zusätzliche Namen:: RNA polymerase II subunit A , POLR2 , POLRA , RPB1 , RPBh1 , RPO2 , RPOL2 , RpIILS , hRPB220 , hsRPB1
Anwendung:: ChIP, Flow Cytometry, WB, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Fish, Human
Buffer:: PBS, no preservatives.
Immunogen:: 10 repeats of synthetic peptide YSPTSPS using chemically synthesized phospho-Ser 5 YSPTSpPS (Human). [UniProt# P24928]
Klon:: 4H8
Uniprot:: P24928
Synonyme:: DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit;DNA-directed RNA polymerase II subunit A;DNA-directed RNA polymerase II subunit RPB1;DNA-directed RNA polymerase III largest subunit;hRPB220;hsRPB1;NEDHIB;POLR2;POLRA;polymerase (RNA) II (DNA directed) polypeptide A, 220kDa;polymerase (RNA) II subunit A;RNA polymerase II subunit B1;RNA-directed RNA polymerase II subunit RPB1;RPB1;RPBh1;RpIILS;RPO2;RPOL2
Weitere Details:: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice