GTX80312
SUN2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX80312
- Zusätzliche Namen:
- Sad1 and UNC84 domain containing 2 , UNC84B
- Anwendung:
- WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Buffer:
- Serum, 0.1% Sodium azide.
- Immunogen:
- Mouse SUN2 residues 1-18
- Uniprot:
- Q9UH99
- Synonyme:
- nuclear envelope protein;protein unc-84 homolog B;rab5-interacting protein;rab5IP;Sad1 unc-84 domain protein 2;sad1/unc-84 protein-like 2;SUN domain-containing protein 2;unc-84 homolog B;UNC84B
- Weitere Details:
- SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]
- Versandbedingungen:
- Blue Ice