PDGF Receptor beta antibody [18A2]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX80295
Zusätzliche Namen:: CD140B , IBGC4 , IMF1 , JTK12 , KOGS , PDGFR , PDGFR1 , PDGFRB , PENTT , platelet derived growth factor receptor beta , PDGF Receptor beta , CD140b , PDGFR beta
Anwendung:: Flow Cytometry, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: 2-8[o]C Do not freeze.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 15mM Sodium azide.
Immunogen:: CD140b-transfected NIH 3T3 cells
Klon:: 18A2
Uniprot:: P09619
Synonyme:: Activated tyrosine kinase PDGFRB;Beta platelet-derived growth factor receptor;beta-type platelet-derived growth factor receptor;CD140 antigen-like family member B;CD140B;IBGC4;IMF1;JTK12;KOGS;NDEL1-PDGFRB;PDGF-R-beta;PDGFR;PDGFR-1;PDGFR-beta;PDGFR1;PENTT;platelet-derived growth factor receptor 1;platelet-derived growth factor receptor beta;platelet-derived growth factor receptor, beta polypeptide
Weitere Details:: The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]

Versandbedingungen:: Blue Ice