CD38 antibody [HIT2] (PE)

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX80118
Zusätzliche Namen:: CD38 molecule , ADPRC 1 , ADPRC1
Anwendung:: Flow Cytometry
Konzentration:: 0.1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C Do not freeze. Protect from light.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: 10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.
Immunogen:: Human thymocytes in foetus
Klon:: HIT2
Uniprot:: P28907
Synonyme:: 2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2'-phospho-cyclic-ADP-ribose transferase;ADP-ribosyl cyclase 1;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;ADPRC 1;ADPRC1;CD38 antigen (p45);cluster of differentiation 38;cyclic ADP-ribose hydrolase 1;ecto-nicotinamide adenine dinucleotide glycohydrolase;NAD(+) nucleosidase;T10
Weitere Details:: The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Versandbedingungen:: Blue Ice