CD177 antibody [MEM-166] (APC)

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX79995
Zusätzliche Namen:: CD177 , CD177 molecule , HNA2A , HNA2a , NB1 , NB1 GP , PRV1
Anwendung:: Flow Cytometry
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Size-exclusion Chromatography
Lagerbedingungen:: 2-8[o]C Do not freeze. Protect from light.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 15mM Sodium azide.
Immunogen:: Human granulocytes
Klon:: MEM-166
Uniprot:: Q8N6Q3
Synonyme:: CD177 antigen;cell surface receptor;HNA-2a;HNA2A;human neutrophil alloantigen 2a;NB1;NB1 glycoprotein;NB1 GP;polycythemia rubra vera protein 1;PRV-1;PRV1
Weitere Details:: This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]