GTX79792
Factor VII antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX79792
- Zusätzliche Namen:
- F7,SPCA,coagulation factor VII,Factor VII,FVII
- Anwendung:
- ELISA, WB
- Konzentration:
- 10 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 50mM Sodium Phosphate, 100mM NaCl, 1mM EDTA, no preservatives.
- Immunogen:
- Full length native protein (purified) (Human).
- Uniprot:
- P08709
- Synonyme:
- coagulation factor VII;coagulation factor VII (serum prothrombin conversion accelerator);eptacog alfa;FVII coagulation protein;proconvertin;Serum prothrombin conversion accelerator;SPCA
- Weitere Details:
- This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]
- Versandbedingungen:
- Blue Ice