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  2. Polyclonal

GTX79668

Protein C antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX79668
Anwendung:
ELISA, WB
Konzentration:
10 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Mouse
Aufreinigung:
Protein G Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Sheep
Reaktivitäten:
Mouse
Buffer:
50mM Sodium Phosphate, 100mM NaCl, 1mM EDTA, no preservatives.
Immunogen:
Full length native protein (purified) (Mouse).
Uniprot:
P33587
Synonyme:
anticoagulant protein C;autoprothrombin IIA;blood coagulation factor XIV;inactivator of coagulation factors Va, VIII;P;PC;vitamin K-dependent protein C
Weitere Details:
This gene encodes the vitamin K-dependent protein C, which plays a vital role in the anticoagulation pathway. The encoded protein undergoes proteolytic processing including activation by thrombin-thrombomodulin complex to form the anticoagulant serine protease that degrades activated coagulation factors. A complete lack of the encoded protein in mice results in severe perinatal consumptive coagulopathy in the brain and liver, resulting in death within 24 hours after birth. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate the mature protein. [provided by RefSeq, Sep 2015]
Versandbedingungen:
Blue Ice