GTX79622
tPA antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX79622
- Zusätzliche Namen:
- PLAT,TPA,plasminogen activator, tissue type,tPA,TPA Tissue Plasminogen Activator
- Anwendung:
- ELISA, WB
- Konzentration:
- 10 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein G Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Sheep
- Reaktivitäten:
- Human, Porcine
- Buffer:
- 50mM Sodium Phosphate, 100mM NaCl, 1mM EDTA, no preservatives.
- Immunogen:
- Recombinant full length wild-type human protein (Glycosylated).
- Uniprot:
- P00750
- Synonyme:
- alteplase;plasminogen/activator kringle;reteplase;T-PA;t-plasminogen activator;tissue-type plasminogen activator;TPA
- Weitere Details:
- This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
- Versandbedingungen:
- Blue Ice