GTX79089
eIF2 alpha (phospho Ser48) antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX79089
- Zusätzliche Namen:
- EIF2,EIF2A,EIF2S1,EIF2alpha,eukaryotic translation initiation factor 2 subunit alpha,eIF2 alpha
- Anwendung:
- IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Sequential Chromatography; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 150mM NaCl, 0.5% BSA, 50% glycerol (Please contact us for BSA-free format), 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized phosphopeptide derived from human eIF2a around the phosphorylation site of Serine 49 (L-L-Sp-E-L).
- Uniprot:
- P05198
- Synonyme:
- EIF-2;eIF-2-alpha;EIF-2A;EIF-2alpha;EIF2;EIF2A;eukaryotic translation initiation factor 2 subunit 1;Eukaryotic translation initiation factor 2 subunit alpha;eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
- Weitere Details:
- The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
- Versandbedingungen:
- Blue Ice