GTX78963
PKR (phospho Thr451) antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX78963
- Zusätzliche Namen:
- EIF2AK1,EIF2AK2,PKR,PPP1R83,PRKR,eukaryotic translation initiation factor 2 alpha kinase 2
- Anwendung:
- IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Sequential Chromatography; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 150mM NaCl, 0.5% BSA, 50% glycerol (Please contact us for BSA-free format), 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized phosphopeptide derived from human PKR around the phosphorylation site of threonine 451 (K-G-Tp-L-R).
- Uniprot:
- P19525
- Synonyme:
- double stranded RNA activated protein kinase;eIF-2A protein kinase 2;EIF2AK1;Eukaryotic translation initiation factor 2-alpha kinase 2;interferon-induced, double-stranded RNA-activated protein kinase;interferon-inducible elF2alpha kinase;Interferon-inducible RNA-dependent protein kinase;LEUDEN;P1/eIF-2A protein kinase;p68 kinase;PKR;PPP1R83;PRKR;protein kinase R;Protein kinase RNA-activated;protein kinase, interferon-inducible double stranded RNA dependent;protein phosphatase 1, regulatory subunit 83;tyrosine-protein kinase EIF2AK2
- Weitere Details:
- The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Versandbedingungen:
- Blue Ice