GTX77874
NCOA62 antibody, N-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX77874
- Zusätzliche Namen:
- SNW domain containing 1 , Bx42 , FUN20 , NCOA-62 , PRPF45 , Prp45 , SKIIP , SKIP , SKIP1
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.5-1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a N-terminal region of Human NCOA62.
- Uniprot:
- Q13573
- Synonyme:
- Bx42;FUN20;homolog of Drosophila BX42;NCOA-62;nuclear protein SkiP;nuclear receptor coactivator NCoA-62;nuclear receptor coactivator, 62-kD;Prp45;PRPF45;SKI interacting protein;ski-interacting protein;SKIIP;SKIP;SKIP1;SNW domain-containing protein 1
- Weitere Details:
- This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
- Versandbedingungen:
- Blue Ice