GTX77851
NFYA antibody, C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX77851
- Zusätzliche Namen:
- nuclear transcription factor Y subunit alpha , CBF-A , CBF-B , HAP2 , NF-YA
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.5-1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a C-terminal region of Human NFYA
- Uniprot:
- P23511
- Synonyme:
- CAAT box DNA-binding protein subunit A;CAAT-box DNA binding protein subunit A;CBF-A;CBF-B;CCAAT-binding transcription factor subunit B;HAP2;HAP2 CCAAT-binding protein;NF-YA;nuclear transcription factor Y subunit A;nuclear transcription factor Y subunit alpha;nuclear transcription factor Y, alpha;Transcription factor NF-Y, A subunit
- Weitere Details:
- The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice