GTX77689
AChR gamma antibody, N-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX77689
- Zusätzliche Namen:
- cholinergic receptor nicotinic gamma subunit , ACHRG
- Anwendung:
- WB
- Konzentration:
- 0.5-1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a N-terminal region of Human AChR gamma
- Uniprot:
- P07510
- Synonyme:
- acetylcholine receptor subunit gamma;acetylcholine receptor, muscle, gamma subunit;acetylcholine receptor, nicotinic, gamma (muscle);ACHRG;cholinergic receptor, nicotinic gamma;cholinergic receptor, nicotinic, gamma (muscle);cholinergic receptor, nicotinic, gamma polypeptide
- Weitere Details:
- The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.[provided by RefSeq, Sep 2009]
- Versandbedingungen:
- Blue Ice