Ku70 antibody [529]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX77607
Zusätzliche Namen:: X-ray repair cross complementing 6 , CTC75 , CTCBF , G22P1 , KU70 , ML8 , TLAA
Anwendung:: WB, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant antigen containing the amino terminal portion of human Ku70 protein
Klon:: 529
Uniprot:: P12956
Synonyme:: 5'-deoxyribose-5-phosphate lyase Ku70;5'-dRP lyase Ku70;70 kDa subunit of Ku antigen;ATP-dependent DNA helicase 2 subunit 1;ATP-dependent DNA helicase II 70 kDa subunit;ATP-dependent DNA helicase II, 70 kDa subunit;CTC box binding factor 75 kDa subunit;CTC box-binding factor 75 kDa subunit;CTC75;CTCBF;DNA repair protein XRCC6;G22P1;Ku autoantigen p70 subunit;Ku autoantigen, 70kDa;KU70;lupus Ku autoantigen protein p70;ML8;thyroid autoantigen 70kD (Ku antigen);thyroid autoantigen 70kDa (Ku antigen);Thyroid-lupus autoantigen;thyroid-lupus autoantigen p70;TLAA;X-ray repair complementing defective repair in Chinese hamster cells 6;X-ray repair cross-complementing protein 6
Weitere Details:: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice