TLR4 antibody [HTA125]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX75742
Zusätzliche Namen:: toll like receptor 4 , ARMD10 , CD284 , TLR-4 , TOLL
Anwendung:: Flow Cytometry, WB, IHC-P, IHC-Fr, IF, ICC, IP, Neutralisation
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Canine, Human, Mouse, Porcine, Feline, Guinea Pig
Buffer:: PBS, 0.09% Sodium azide.
Immunogen:: Ba/F3 cell line expressing TLR4 (CD284).
Klon:: HTA125
Uniprot:: O00206
Synonyme:: ARMD10;CD284;homolog of Drosophila toll;hToll;TLR-4;TOLL;toll like receptor 4 protein;toll-like receptor 4
Weitere Details:: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Versandbedingungen:: Blue Ice