CDK6 antibody [DCS 83.1]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX75692
Zusätzliche Namen:: cyclin dependent kinase 6 , MCPH12 , PLSTIRE
Anwendung:: WB, IHC-Fr, IP
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.08% Sodium azide.
Immunogen:: Recombinant cdk6 protein
Klon:: DCS 83.1
Uniprot:: Q00534
Synonyme:: cell division protein kinase 6;cyclin-dependent kinase 6;MCPH12;PLSTIRE;serine/threonine-protein kinase PLSTIRE
Weitere Details:: The protein encoded by this gene is a member of the CMGC family of serine/threonine protein kinases. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Altered expression of this gene has been observed in multiple human cancers. A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly. [provided by RefSeq, Aug 2017]

Versandbedingungen:: Blue Ice