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GTX74581
CD38 antibody [AT13/5] (PE)
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX74581
- Zusätzliche Namen:
- CD38 molecule , ADPRC 1 , ADPRC1
- Anwendung:
- Flow Cytometry
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, 1% BSA, 0.09% Sodium azide.
- Immunogen:
- Namalwa human B-cell line.
- Klon:
- AT13/5
- Uniprot:
- P28907
- Synonyme:
- 2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2'-phospho-cyclic-ADP-ribose transferase;ADP-ribosyl cyclase 1;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;ADPRC 1;ADPRC1;CD38 antigen (p45);cluster of differentiation 38;cyclic ADP-ribose hydrolase 1;ecto-nicotinamide adenine dinucleotide glycohydrolase;NAD(+) nucleosidase;T10
- Weitere Details:
- The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
- Versandbedingungen:
- Blue Ice