CD43 antibody [DF-T1]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX73633
Zusätzliche Namen:: sialophorin , CD43 , GALGP , GPL115 , LSN
Anwendung:: IHC-P
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Purified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.09% Sodium azide.
Immunogen:: BALB/C mice were immunized with myeloblast cell line KG1.
Klon:: DF-T1
Uniprot:: P16150
Synonyme:: 3E8 antigen;A630014B01Rik;B-cell differentiation antigen LP-3;CD43;Ga;galactoglycoprotein;GALGP;GPL115;leu;leukocyte sialoglycoprotein;leukosialin;LSN;Ly-4;Ly-48;Ly4;Ly48;lymphocyte antigen 48;Sialophorin;sialophorin (gpL115, leukosialin, CD43)
Weitere Details:: This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]

Versandbedingungen:: Blue Ice