GTX71717
mGluR7 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX71717
- Zusätzliche Namen:
- GLUR7 , GPRC1G , GRM7 , MGLU7 , MGLUR7 , PPP1R87 , glutamate metabotropic receptor 7 , mGluR7 , Metabotropic Glutamate Receptor 7
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Bovine, Human
- Buffer:
- PBS, 0.1% Sodium azide.
- Immunogen:
- Synthetic 19 amino acid peptide from N-terminal extracellular domain of human GRM7 / MGLUR7.
- Uniprot:
- Q14831
- Synonyme:
- GLUR7;glutamate receptor, metabotropic 7;GPRC1G;metabotropic glutamate receptor 7;MGLU7;MGLUR7;NEDSHBA;PPP1R87;protein phosphatase 1, regulatory subunit 87
- Weitere Details:
- L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
- Versandbedingungen:
- Blue Ice