GTX70455
PUMA antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX70455
- Zusätzliche Namen:
- Bcl2 Binding Component 3 , Jfy-1 , Jfy1 , Puma , Bbc3
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- BCL2 binding component 3
- Synonyme:
- bcl-2-binding component 3;JFY-1;JFY1;p53 up-regulated modulator of apoptosis;p53-upregulated modulator of apoptosis;PUMA
- Weitere Details:
- A novel gene PUMA (p53 upregulated modulator of apoptosis) is a target for activation by the p53 tumor-suppressor gene. p53 functions as a transcriptional activator, and influences p53-inducible genes that play a role in the induction of apoptosis in response to p53. Antisense inhibition of PUMA expression reduced the apoptotic response to p53, and PUMA is likely to play a role in mediating p53-induced cell death through the cytochrome c/Apaf-1-dependent pathway.
- Versandbedingungen:
- Blue Ice