GTX70310
53BP1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX70310
- Zusätzliche Namen:
- tumor protein p53 binding protein 1 , 53BP1 , TDRD30 , p202 , p53BP1
- Anwendung:
- IHC, WB, IHC-P, IF, ICC
- Konzentration:
- 0.94 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Synthetic peptide corresponding to the carboxy-terminus of h53BP1, conjugated to a carrier protein.
- Uniprot:
- Q12888
- Synonyme:
- 53BP1;p202;p53-binding protein 1;p53BP1;TDRD30;TP53-binding protein 1;tumor protein 53-binding protein, 1;tumor suppressor p53-binding protein 1
- Weitere Details:
- P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
- Versandbedingungen:
- Blue Ice