RbAp48 antibody [11G10]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX70232
Zusätzliche Namen:: RB binding protein 4, chromatin remodeling factor , NURF55 , RBAP48 , lin-53
Anwendung:: ChIP, IHC, WB, IHC-P, IF, ICC, IP, FuncS, Neutralisation
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: PBS, no preservatives.
Immunogen:: The complete coding region (amino acids 1-425) of RbAp48 expressed in E. coli.
Klon:: 11G10
Uniprot:: Q09028
Synonyme:: CAF-1 subunit C;CAF-I 48 kDa subunit;CAF-I p48;chromatin assembly factor 1 subunit C;chromatin assembly factor I p48 subunit;chromatin assembly factor/CAF-1 p48 subunit;histone-binding protein RBBP4;lin-53;MSI1 protein homolog;nucleosome-remodeling factor subunit RBAP48;NURF55;RBAP48;RBBP-4;retinoblastoma-binding protein 4;retinoblastoma-binding protein p48
Weitere Details:: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Versandbedingungen:: Blue Ice