GTX68611-PRO
Human TDP1 protein, His tag
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX68611-PRO
- Zusätzliche Namen:
- tyrosyl-DNA phosphodiesterase 1
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM Tris-HCl, 0.4M Urea, 10% Glycerol, no preservatives.
- Immunogen:
- tyrosyl-DNA phosphodiesterase 1
- Spezies:
- Human
- Uniprot:
- Q9BRS7
- Synonyme:
- tyr-DNA phosphodiesterase 1;tyrosyl-DNA phosphodiesterase 1
- Weitere Details:
- The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). [provided by RefSeq, Aug 2016]
- Versandbedingungen:
- Dry Ice