GTX68514-PRO
Human GSKIP protein, His tag
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX68514-PRO
- Zusätzliche Namen:
- GSK3B interacting protein , C14orf129 , HSPC210
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM Tris-HCl, 50mM NaCl, 10% Glycerol, 1mM DTT, no preservatives.
- Immunogen:
- GSK3B interacting protein
- Spezies:
- Human
- Uniprot:
- Q9P0R6
- Synonyme:
- C14orf129;GSK3-beta interaction protein;GSK3B-interacting protein;GSK3beta interaction protein;HSPC210
- Weitere Details:
- This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
- Versandbedingungen:
- Dry Ice