GTX68421-PRO
Human DCPS protein, His tag
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX68421-PRO
- Zusätzliche Namen:
- decapping enzyme, scavenger , ARS , DCS1 , HINT-5 , HINT5 , HSL1 , HSPC015
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM Tris-HCl, 20% Glycerol, 1mM DTT, no preservatives.
- Immunogen:
- decapping enzyme, scavenger
- Spezies:
- Human
- Uniprot:
- Q96C86
- Synonyme:
- 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase;ARS;DCS-1;DCS1;decapping scavenger enzyme;epididymis secretory sperm binding protein;heat shock-like protein 1;HINT-5;hint-related 7meGMP-directed hydrolase;HINT5;histidine triad nucleotide-binding protein 5;histidine triad protein member 5;homolog of C. elegans 7meGMP-directed hydrolase dcs-1;HSL1;HSPC015;m7GpppX diphosphatase;mRNA decapping enzyme;scavenger mRNA-decapping enzyme DcpS
- Weitere Details:
- This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover. [provided by RefSeq, Apr 2017]
- Versandbedingungen:
- Dry Ice