GTX68332-PRO
Human RASD2 protein, His tag
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX68332-PRO
- Zusätzliche Namen:
- RASD family member 2 , Rhes , TEM2
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM Tris-HCl, 10% Glycerol, no preservatives.
- Immunogen:
- RASD family member 2
- Spezies:
- Human
- Uniprot:
- Q96D21
- Synonyme:
- GTP-binding protein Rhes;Ras homolog enriched in striatum;Rhes;TEM2;tumor endothelial marker 2
- Weitere Details:
- This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. [provided by RefSeq, Jan 2016]
- Versandbedingungen:
- Dry Ice