GTX68231-PRO
Human NUDT5 protein, His tag
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX68231-PRO
- Zusätzliche Namen:
- nudix hydrolase 5 , YSA1 , YSA1H , YSAH1 , hNUDT5
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM Tris-HCl, 100mM NaCl, 10% Glycerol, 1mM DTT, no preservatives.
- Immunogen:
- nudix hydrolase 5
- Spezies:
- Human
- Uniprot:
- Q9UKK9
- Synonyme:
- 8-oxo-dGDP phosphatase;ADP-sugar pyrophosphatase;hNUDT5;nuclear ATP-synthesis protein NUDIX5;Nucleoside diphosphate-linked moiety X motif 5;nudix (nucleoside diphosphate linked moiety X)-type motif 5;YSA1;YSA1H;YSAH1
- Weitere Details:
- This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013]
- Versandbedingungen:
- Dry Ice