GTX68166-PRO
Human RNAse H2A protein, His tag
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX68166-PRO
- Zusätzliche Namen:
- ribonuclease H2 subunit A , AGS4 , JUNB , RNASEHI , RNHIA , RNHL , THSD8
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM Tris-HCl, 0.4M Urea, 10% Glycerol, no preservatives.
- Immunogen:
- ribonuclease H2 subunit A
- Spezies:
- Human
- Uniprot:
- O75792
- Synonyme:
- AGS4;aicardi-Goutieres syndrome 4 protein;JUNB;ribonuclease H2 subunit A;ribonuclease H2, large subunit;ribonuclease HI large subunit;ribonuclease HI subunit A;RNase H(35);RNase H2 subunit A;RNase HI large subunit;RNASEHI;RNHIA;RNHL;THSD8
- Weitere Details:
- The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]
- Versandbedingungen:
- Dry Ice