GTX68083-PRO
Human RNF7 protein, His tag
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX68083-PRO
- Zusätzliche Namen:
- ring finger protein 7 , CKBBP1 , ROC2 , SAG , rbx2
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM Tris-HCl, 0.4M Urea, 10% Glycerol, no preservatives.
- Immunogen:
- ring finger protein 7
- Spezies:
- Human
- Uniprot:
- Q9UBF6
- Synonyme:
- CKBBP1;CKII beta-binding protein 1;rbx2;regulator of cullins 2;RING finger protein 7;RING-box protein 2;ROC2;SAG;sensitive to apoptosis gene protein;sensitive to apoptosis, zinc RING finger protein SAG, regulator of cullins 2;zinc RING finger protein SAG
- Weitere Details:
- The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Dry Ice