GTX68068-PRO
Human PSMF1 protein, His tag
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX68068-PRO
- Zusätzliche Namen:
- proteasome inhibitor subunit 1 , PI31
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM Tris-HCl, 20% Glycerol, 1mM DTT, 0.1mM PMSF, no preservatives.
- Immunogen:
- proteasome inhibitor subunit 1
- Spezies:
- Human
- Uniprot:
- Q92530
- Synonyme:
- PI31;proteasome (prosome, macropain) inhibitor subunit 1 (PI31);proteasome inhibitor PI31 subunit
- Weitere Details:
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Dry Ice