GTX67917-PRO
Human UBE2D2 protein
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX67917-PRO
- Zusätzliche Namen:
- ubiquitin conjugating enzyme E2 D2 , E2(17)KB2 , PUBC1 , UBC4 , UBC4/5 , UBCH4 , UBCH5B
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM MES buffer, 50mM NaCl, 1mM DTT, no preservatives.
- Immunogen:
- ubiquitin conjugating enzyme E2 D2
- Spezies:
- Human
- Uniprot:
- P62837
- Synonyme:
- (E3-independent) E2 ubiquitin-conjugating enzyme D2;E2 ubiquitin-conjugating enzyme D2;E2(17)KB2;p53-regulated ubiquitin-conjugating enzyme 1;PUBC1;UBC4;UBC4/5;UBCH4;UBCH5B;ubiquitin carrier protein D2;ubiquitin conjugating enzyme E2D 2;ubiquitin-conjugating enzyme E2 D2;ubiquitin-conjugating enzyme E2-17 kDa 2;Ubiquitin-conjugating enzyme E2(17)KB 2;ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5);ubiquitin-protein ligase D2
- Weitere Details:
- Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
- Versandbedingungen:
- Dry Ice