Human alpha Synuclein protein

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX67834-PRO
Zusätzliche Namen:: synuclein alpha , NACP , PARK1 , PARK4 , PD1
Physischer Zustand:: Lyophilized
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles.
Hersteller:: Genetex
Buffer:: Reconstitute with ddH₂O but not less than 100 ug/ml. Lyophilized from 0.2um-filtered 20mM Tris-HCl buffer (pH7.5), 100mM NaCl, 1mM MgCl₂, no preservatives.
Immunogen:: synuclein alpha
Spezies:: Human
Uniprot:: P37840
Synonyme:: alpha-synuclein;I+/--synuclein;NACP;non A-beta component of AD amyloid;Non-A beta component of AD amyloid;Non-A4 component of amyloid precursor;PARK1;PARK4;PD1;synuclein alpha-140;synuclein, alpha (non A4 component of amyloid precursor);truncated alpha synuclein
Weitere Details:: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]