GTX67601-PRO
Human OAS1 protein, His tag
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX67601-PRO
- Zusätzliche Namen:
- 2'-5'-oligoadenylate synthetase 1 , E18/E16 , IFI-4 , OIAS , OIASI
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM Tris-HCl, 10% Glycerol, 1mM DTT, no preservatives.
- Immunogen:
- 2'-5'-oligoadenylate synthetase 1
- Spezies:
- Human
- Uniprot:
- P00973
- Synonyme:
- (2-5')oligo(A) synthase 1;2-5A synthase 1;2-5A synthetase 1;2'-5'-oligoadenylate synthase 1;2'-5'-oligoadenylate synthetase 1, 40/46kDa;2'-5'-oligoisoadenylate synthetase 1;2',5'-oligo A synthetase 1;E16 (2'-5') oligo A synthetase;E18/E16;IFI-4;OIAS;OIASI;p46/p42 OAS
- Weitere Details:
- This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12. [provided by RefSeq, Feb 2016]
- Versandbedingungen:
- Dry Ice