GTX67355-PRO
Human TIMM8A protein, His tag
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX67355-PRO
- Zusätzliche Namen:
- translocase of inner mitochondrial membrane 8A , DDP , DDP1 , DFN1 , MTS , TIM8
- Konzentration:
- 0.25 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM Tris-HCl, 150mM NaCl, 30% Glycerol, 1mM DTT, no preservatives.
- Immunogen:
- translocase of inner mitochondrial membrane 8A
- Spezies:
- Human
- Uniprot:
- O60220
- Synonyme:
- DDP;DDP1;deafness dystonia protein 1;deafness/dystonia peptide;DFN1;mitochondrial import inner membrane translocase subunit Tim8 A;MTS;TIM8;translocase of inner mitochondrial membrane 8 homolog A;X-linked deafness dystonia protein
- Weitere Details:
- This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2009]
- Versandbedingungen:
- Dry Ice