GTX67023-PRO
Human GPI protein, His tag (active)
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX67023-PRO
- Zusätzliche Namen:
- glucose-6-phosphate isomerase , AMF , GNPI , NLK , PGI , PHI , SA-36 , SA36
- Anwendung:
- FuncS
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM Tris-HCl, 10% Glycerol, 1mM DTT, no preservatives.
- Immunogen:
- glucose-6-phosphate isomerase
- Spezies:
- Human
- Uniprot:
- P06744
- Synonyme:
- AMF;autocrine motility factor;glucose-6-phosphate isomerase;GNPI;hexose monophosphate isomerase;hexosephosphate isomerase;neuroleukin;NLK;oxoisomerase;PGI;PHI;phosphoglucose isomerase;phosphohexomutase;phosphohexose isomerase;phosphosaccharomutase;SA-36;SA36;Sperm antigen 36;sperm antigen-36
- Weitere Details:
- This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
- Versandbedingungen:
- Dry Ice