GTX66933-PRO
Human CA8 protein, His tag (active)
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX66933-PRO
- Zusätzliche Namen:
- carbonic anhydrase 8 , CA-RP , CA-VIII , CALS , CAMRQ3 , CARP
- Anwendung:
- FuncS
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM Tris-HCl, 20% Glycerol, 1mM DTT, no preservatives.
- Immunogen:
- carbonic anhydrase 8
- Spezies:
- Human
- Uniprot:
- P35219
- Synonyme:
- CA-related protein;CA-RP;CA-VIII;CALS;CAMRQ3;carbonate dehydratase;carbonic anhydrase VIII;carbonic anhydrase-like sequence;carbonic anhydrase-related protein;CARP
- Weitere Details:
- The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
- Versandbedingungen:
- Dry Ice