GTX66870
TWEAK antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX66870
- Zusätzliche Namen:
- TNF superfamily member 12 , APO3L , DR3LG , TNLG4A , TWEAK
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.05% Sodium azide.
- Immunogen:
- Synthetic peptide, corresponding to amino acids 51-100 of Human TWEAK.
- Uniprot:
- O43508
- Synonyme:
- APO3 ligand;APO3/DR3 ligand;APO3L;DR3LG;TNF-related WEAK inducer of apoptosis;TNFSF12-TNFSF13 protein;TNLG4A;tumor necrosis factor (ligand) superfamily, member 12;tumor necrosis factor (ligand) superfamily, member 12-member 13;tumor necrosis factor ligand 4A;tumor necrosis factor ligand superfamily member 12;tumor necrosis factor superfamily member 12;TWE-PRIL;TWEAK
- Weitere Details:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
- Versandbedingungen:
- Blue Ice