ZAP70 antibody [4B2]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX66846
Zusätzliche Namen:: zeta chain of T cell receptor associated protein kinase 70 , ADMIO2 , IMD48 , SRK , STCD , STD , TZK , ZAP-70
Anwendung:: WB, IP
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: 100mM Tris-Glycine, 150mM NaCl, 50% Glycerol, 0.2% Sodium azide.
Immunogen:: Purified recombinant human ZAP70 protein fragments expressed in E.coli.
Klon:: 4B2
Uniprot:: P43403
Synonyme:: 70 kDa zeta-associated protein;70 kDa zeta-chain associated protein;ADMIO2;IMD48;SRK;STCD;STD;syk-related tyrosine kinase;tyrosine-protein kinase ZAP-70;TZK;ZAP-70;zeta chain of T cell receptor associated protein kinase 70kDa;zeta-chain (TCR) associated protein kinase 70kDa;zeta-chain associated protein kinase, 70kD
Weitere Details:: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice