BRG1 antibody [6D7]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX66842
Zusätzliche Namen:: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 , BAF190 , BAF190A , BRG1 , CSS4 , MRD16 , RTPS2 , SNF2 , SNF2L4 , SNF2LB , SWI2 , hSNF2b
Anwendung:: WB, IF, ICC, IP
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: 100mM Tris-Glycine, 150mM NaCl, 50% Glycerol, 0.2% Sodium azide.
Immunogen:: Purified recombinant human SMARCA4 protein fragments expressed in E.coli.
Klon:: 6D7
Uniprot:: P51532
Synonyme:: ATP-dependent helicase SMARCA4;BAF190;BAF190A;brahma protein-like 1;BRG1;BRG1-associated factor 190A;BRM/SWI2-related gene 1;CSS4;global transcription activator homologous sequence;homeotic gene regulator;hSNF2b;mitotic growth and transcription activator;MRD16;nuclear protein GRB1;protein brahma homolog 1;protein BRG-1;RTPS2;SNF2;SNF2-beta;SNF2-like 4;SNF2L4;SNF2LB;sucrose nonfermenting-like 4;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4;SWI2;transcription activator BRG1
Weitere Details:: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Versandbedingungen:: Blue Ice