GTX66633
TRADD antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX66633
- Zusätzliche Namen:
- TNFRSF1A associated via death domain , Hs.89862
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 15mM Sodium azide.
- Immunogen:
- Synthetic peptide, corresponding to amino acids 250-304 of Human TRADD.
- Uniprot:
- Q15628
- Synonyme:
- Hs.89862;TNFR1-associated death domain protein;TNFRSF1A-associated via death domain;tumor necrosis factor receptor type 1 associated death domain protein;tumor necrosis factor receptor type 1-associated DEATH domain protein;tumor necrosis factor receptor-1-associated protein
- Weitere Details:
- The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice