Proteasome 20S beta 3 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX66592
Zusätzliche Namen:: proteasome subunit beta 3 , HC10-II
Anwendung:: WB, IHC-P
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Recombinant funsion protein containing a sequence corresponding to amino acids 1-205 of human PSMB3 (NP_002786.2).
Uniprot:: P49720
Synonyme:: epididymis secretory sperm binding protein;HC10-II;proteasome (prosome, macropain) subunit, beta type, 3;proteasome chain 13;proteasome component C10-II;proteasome subunit beta 3;proteasome subunit beta type-3;proteasome theta chain
Weitere Details:: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion, a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12. Alternative splicing results in multiple transcript variants [provided by RefSeq, Sep 2013]

Versandbedingungen:: Blue Ice