GTX66538
Fnk antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX66538
- Zusätzliche Namen:
- polo like kinase 3 , CNK , FNK , PLK-3 , PRK
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 487-646 of human PLK3 (NP_004064.2).
- Uniprot:
- Q9H4B4
- Synonyme:
- CNK;cytokine-inducible serine/threonine-protein kinase;FGF-inducible kinase;FNK;PLK-3;Polo-like kinase 3;PRK;proliferation-related kinase;serine/threonine-protein kinase PLK3
- Weitere Details:
- The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis. [provided by RefSeq, Sep 2015]
- Versandbedingungen:
- Blue Ice