GTX66473
METAP2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX66473
- Zusätzliche Namen:
- methionyl aminopeptidase 2 , MAP2 , MNPEP , p67eIF2
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 1-220 of human METAP2 (NP_006829.1).
- Uniprot:
- P50579
- Synonyme:
- eIF-2-associated p67 homolog;initiation factor 2-associated 67 kDa glycoprotein;MAP2;methionine aminopeptidase 2;MNPEP;p67eIF2;Peptidase M;peptidase M 2;testicular tissue protein Li 17
- Weitere Details:
- The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
- Versandbedingungen:
- Blue Ice