GTX66438
APPBP1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX66438
- Zusätzliche Namen:
- NEDD8 activating enzyme E1 subunit 1 , A-116A10.1 , APPBP1 , HPP1 , ula-1
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 1-220 of human NAE1 (NP_003896.1).
- Uniprot:
- Q13564
- Synonyme:
- A-116A10.1;amyloid beta precursor protein binding protein 1, 59kDa;amyloid beta precursor protein-binding protein 1, 59 kDa;amyloid beta precursor protein-binding protein 1, 59kD;amyloid protein-binding protein 1;APP-BP1;APPBP1;HPP1;NEDD8-activating enzyme E1 regulatory subunit;NEDD8-activating enzyme E1 subunit;proto-oncogene protein 1;protooncogene protein 1;ula-1
- Weitere Details:
- The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice