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  2. Polyclonal

GTX66367

EEF1E1 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX66367
Zusätzliche Namen:
eukaryotic translation elongation factor 1 epsilon 1 , AIMP3 , P18
Anwendung:
WB, IF, ICC
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human EEF1E1 (NP_004271.1).
Uniprot:
O43324
Synonyme:
AIMP3;aminoacyl tRNA synthetase complex-interacting multifunctional protein 3;ARS-interacting multifunctional protein 3;Elongation factor p18;eukaryotic translation elongation factor 1 epsilon-1;multisynthase complex auxiliary component p18;P18;p18 component of aminoacyl-tRNA synthetase complex
Weitere Details:
This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010]
Versandbedingungen:
Blue Ice