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  1. Alles ansehen
  2. Polyclonal

GTX66303

PSCD4 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX66303
Zusätzliche Namen:
cytohesin 4 , CYT4 , DJ63G5.1 , PSCD4 , cytohesin-4
Anwendung:
WB
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human, Mouse
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Mouse, Rat
Buffer:
PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
Recombinant funsion protein containing a sequence corresponding to amino acids 1-70 of human CYTH4 (NP_037517.1).
Uniprot:
Q9UIA0
Synonyme:
CYT4;cytohesin-4;DJ63G5.1;PH, SEC7 and coiled-coil domain-containing protein 4;pleckstrin homology, Sec7 and coiled/coil domains 4;PSCD4
Weitere Details:
This gene encodes a member of the PSCD family of proteins, which have an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family function as GEPs for ADP-ribosylation factors (ARFs), which are guanine nucleotide-binding proteins involved in vesicular trafficking pathways. This protein exhibits GEP activity in vitro with ARF1 and ARF5, but is inactive with ARF6. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
Versandbedingungen:
Blue Ice