GTX66282
B4GALT4 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX66282
- Zusätzliche Namen:
- beta-1,4-galactosyltransferase 4 , B4Gal-T4 , beta4Gal-T4
- Anwendung:
- WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 35-344 of human B4GALT4 (NP_003769.1).
- Uniprot:
- O60513
- Synonyme:
- B4Gal-T4;beta-1,4-galactosyltransferase 4;beta-1,4-GalTase 4;beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 4;beta4Gal-T4;lactotriaosylceramide beta-1,4-galactosyltransferase;N-acetyllactosamine synthase;nal synthase;UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4;UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 4;UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4;UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4
- Weitere Details:
- This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice