GTX66229
PTPN22 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX66229
- Zusätzliche Namen:
- protein tyrosine phosphatase non-receptor type 22 , LYP , LYP1 , LYP2 , PEP , PTPN22.5 , PTPN22.6 , PTPN8
- Anwendung:
- WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 1-90 of human PTPN22 (NP_036543.4).
- Uniprot:
- Q9Y2R2
- Synonyme:
- hematopoietic cell protein-tyrosine phosphatase 70Z-PEP;Lymphoid phosphatase;lymphoid-specific protein tyrosine phosphatase;LYP;LYP1;LYP2;PEP;PEST-domain phosphatase;protein tyrosine phosphatase, non-receptor type 22 (lymphoid);protein tyrosine phosphatase, non-receptor type 8;PTPN22.5;PTPN22.6;PTPN8;tyrosine-protein phosphatase non-receptor type 22
- Weitere Details:
- This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009]
- Versandbedingungen:
- Blue Ice